Synthesis of aminoacylated ergosterols: A new lipid component of fungi

Daisuke Yokokawa, Shunsuke Tatematsu, Ryoka Takagi, Yusuke Saga, Hervé Roy, Frédéric Fischer, Hubert D. Becker, Tetsuo Kushiro

研究成果: Article査読

1 被引用数 (Scopus)

抄録

Aminoacylated ergosterol such as 1-ergosteryl aspartate (Erg-Asp) is a new lipid component recently discovered in fungi. In order to study physiological functions of this novel sterol derivative and to develop potential antifungal agents, we established the method to synthesize aminoacylated ergosterol derivatives. Herein, we report the synthesis of Erg-Asp as well as some other aminoacylated ergosterols (Erg-Gly, Erg-Ala, Erg-Leu, Erg-Ile, and Erg-Val) using Boc protected amino acids.

本文言語English
論文番号108823
ジャーナルSteroids
169
DOI
出版ステータスPublished - 5月 2021

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