Ring-opening bulk polymerization of L-lactide in porous hydroxyapatite

Nami Sugiyama, Ryoko Kunibu, Masahiro Yoshizawa-Fujita, Yuko Takeoka, Mamoru Aizawa, Masahiro Rikukawa

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Abstract

Poly(L-lactide) (PLLA) has been synthesized by ring-opening bulk polymerization of L-lactide in porous hydroxyapatite (HAp) matrix without any additional catalyst, and this hybridizing process directly provided artificial bone materials. The obtained PLLA/HAp composites had enough mechanical properties with a bending strength of 53.7 MPa, which was 2.3 times stronger than porous HAp, and showed excellent biocompatibility for clinical applications.

Original languageEnglish
Pages (from-to)1476-1477
Number of pages2
JournalChemistry Letters
Volume36
Issue number12
DOIs
Publication statusPublished - 5 Dec 2007

Cite this

Sugiyama, N., Kunibu, R., Yoshizawa-Fujita, M., Takeoka, Y., Aizawa, M., & Rikukawa, M. (2007). Ring-opening bulk polymerization of L-lactide in porous hydroxyapatite. Chemistry Letters, 36(12), 1476-1477. https://doi.org/10.1246/cl.2007.1476