Oral and extra-oral taste perception

Kurumi Yamamoto, Yoshiro Ishimaru

Research output: Contribution to journalReview articlepeer-review

59 Citations (Scopus)

Abstract

Of the five basic taste qualities, the molecular mechanisms underlying sweet, bitter, and umami (savory) taste perception have been extensively elucidated, including the taste receptors and downstream signal transduction molecules. Recent studies have revealed that these taste-related molecules play important roles not only in the oral cavity but also in a variety of tissues including the respiratory tract, stomach, intestines, pancreas, liver, kidney, testes, and brain. This review covers the current knowledge regarding the physiological roles of taste-related molecules in the oral and extra-oral tissues.

Original languageEnglish
Pages (from-to)240-246
Number of pages7
JournalSeminars in Cell and Developmental Biology
Volume24
Issue number3
DOIs
Publication statusPublished - Mar 2013

Keywords

  • Brush cell
  • Endocrine cell
  • Incretin
  • Insulin
  • Taste receptor

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