Development of nitrogen-doped hydroxyapatite ceramics

Nao Kaneko, Yuhei Suzuki, Ryo Umeda, Ryota Namiki, Chihiro Izawa, Tomoko Ikeda Fukazawa, Michiyo Honda, Takahiro Takei, Tomoaki Watanabe, Mamoru Aizawa

Research output: Contribution to journalArticle

Abstract

Hydroxyapatite (Ca10(PO4)6(OH)2; HAp) is widely used as a biomaterial due to its high biocompatibility. However, biological apatite present in bone and teeth contains various ions in the HAp crystal structure. Thus, biological apatite has many strains and defects, which may impart high osteoconductivity to apatite. To clarify the effects of the strain and/or defects in the HAp crystal structure on the bioactivity, nitrogen-doped (N-doped) HAp ceramics were fabricated by heating pure HAp ceramics. This N-doped method is well-known as a technique to modify the chemical structure at the surface. Some properties of the N-doped HAp ceramics were examined for optimization of the heating temperature. N-doped HAp ceramics fabricated by heating at 850°C in an NH3 atmosphere had N2O molecules in the crystal structure. Therefore, the N-doped HAp ceramics fabricated by the N-doping method have a rare molecule-substitution structure. In conclusion, we have developed the N-doped HAp ceramics which have a rare molecule-substitution structure.

Original languageEnglish
JournalJournal of Asian Ceramic Societies
DOIs
Publication statusAccepted/In press - 1 Jan 2020

Fingerprint

Apatites
Apatite
Durapatite
Hydroxyapatite
Nitrogen
Crystal structure
Heating
Molecules
Substitution reactions
Defects
Biocompatible Materials
Bioactivity
Biocompatibility
Biomaterials
Bone
Doping (additives)
Ions
Temperature

Keywords

  • Hydroxyapatite
  • nitrogen-doping process
  • thermogravimetry mass spectrometry

Cite this

Kaneko, N., Suzuki, Y., Umeda, R., Namiki, R., Izawa, C., Fukazawa, T. I., ... Aizawa, M. (Accepted/In press). Development of nitrogen-doped hydroxyapatite ceramics. Journal of Asian Ceramic Societies. https://doi.org/10.1080/21870764.2020.1712799
Kaneko, Nao ; Suzuki, Yuhei ; Umeda, Ryo ; Namiki, Ryota ; Izawa, Chihiro ; Fukazawa, Tomoko Ikeda ; Honda, Michiyo ; Takei, Takahiro ; Watanabe, Tomoaki ; Aizawa, Mamoru. / Development of nitrogen-doped hydroxyapatite ceramics. In: Journal of Asian Ceramic Societies. 2020.
@article{93293d2ce13842198e6df5532c03fb80,
title = "Development of nitrogen-doped hydroxyapatite ceramics",
abstract = "Hydroxyapatite (Ca10(PO4)6(OH)2; HAp) is widely used as a biomaterial due to its high biocompatibility. However, biological apatite present in bone and teeth contains various ions in the HAp crystal structure. Thus, biological apatite has many strains and defects, which may impart high osteoconductivity to apatite. To clarify the effects of the strain and/or defects in the HAp crystal structure on the bioactivity, nitrogen-doped (N-doped) HAp ceramics were fabricated by heating pure HAp ceramics. This N-doped method is well-known as a technique to modify the chemical structure at the surface. Some properties of the N-doped HAp ceramics were examined for optimization of the heating temperature. N-doped HAp ceramics fabricated by heating at 850°C in an NH3 atmosphere had N2O molecules in the crystal structure. Therefore, the N-doped HAp ceramics fabricated by the N-doping method have a rare molecule-substitution structure. In conclusion, we have developed the N-doped HAp ceramics which have a rare molecule-substitution structure.",
keywords = "Hydroxyapatite, nitrogen-doping process, thermogravimetry mass spectrometry",
author = "Nao Kaneko and Yuhei Suzuki and Ryo Umeda and Ryota Namiki and Chihiro Izawa and Fukazawa, {Tomoko Ikeda} and Michiyo Honda and Takahiro Takei and Tomoaki Watanabe and Mamoru Aizawa",
year = "2020",
month = "1",
day = "1",
doi = "10.1080/21870764.2020.1712799",
language = "English",
journal = "Journal of Asian Ceramic Societies",
issn = "2187-0764",
publisher = "Taylor and Francis Ltd.",

}

Development of nitrogen-doped hydroxyapatite ceramics. / Kaneko, Nao; Suzuki, Yuhei; Umeda, Ryo; Namiki, Ryota; Izawa, Chihiro; Fukazawa, Tomoko Ikeda; Honda, Michiyo; Takei, Takahiro; Watanabe, Tomoaki; Aizawa, Mamoru.

In: Journal of Asian Ceramic Societies, 01.01.2020.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Development of nitrogen-doped hydroxyapatite ceramics

AU - Kaneko, Nao

AU - Suzuki, Yuhei

AU - Umeda, Ryo

AU - Namiki, Ryota

AU - Izawa, Chihiro

AU - Fukazawa, Tomoko Ikeda

AU - Honda, Michiyo

AU - Takei, Takahiro

AU - Watanabe, Tomoaki

AU - Aizawa, Mamoru

PY - 2020/1/1

Y1 - 2020/1/1

N2 - Hydroxyapatite (Ca10(PO4)6(OH)2; HAp) is widely used as a biomaterial due to its high biocompatibility. However, biological apatite present in bone and teeth contains various ions in the HAp crystal structure. Thus, biological apatite has many strains and defects, which may impart high osteoconductivity to apatite. To clarify the effects of the strain and/or defects in the HAp crystal structure on the bioactivity, nitrogen-doped (N-doped) HAp ceramics were fabricated by heating pure HAp ceramics. This N-doped method is well-known as a technique to modify the chemical structure at the surface. Some properties of the N-doped HAp ceramics were examined for optimization of the heating temperature. N-doped HAp ceramics fabricated by heating at 850°C in an NH3 atmosphere had N2O molecules in the crystal structure. Therefore, the N-doped HAp ceramics fabricated by the N-doping method have a rare molecule-substitution structure. In conclusion, we have developed the N-doped HAp ceramics which have a rare molecule-substitution structure.

AB - Hydroxyapatite (Ca10(PO4)6(OH)2; HAp) is widely used as a biomaterial due to its high biocompatibility. However, biological apatite present in bone and teeth contains various ions in the HAp crystal structure. Thus, biological apatite has many strains and defects, which may impart high osteoconductivity to apatite. To clarify the effects of the strain and/or defects in the HAp crystal structure on the bioactivity, nitrogen-doped (N-doped) HAp ceramics were fabricated by heating pure HAp ceramics. This N-doped method is well-known as a technique to modify the chemical structure at the surface. Some properties of the N-doped HAp ceramics were examined for optimization of the heating temperature. N-doped HAp ceramics fabricated by heating at 850°C in an NH3 atmosphere had N2O molecules in the crystal structure. Therefore, the N-doped HAp ceramics fabricated by the N-doping method have a rare molecule-substitution structure. In conclusion, we have developed the N-doped HAp ceramics which have a rare molecule-substitution structure.

KW - Hydroxyapatite

KW - nitrogen-doping process

KW - thermogravimetry mass spectrometry

UR - http://www.scopus.com/inward/record.url?scp=85077872147&partnerID=8YFLogxK

U2 - 10.1080/21870764.2020.1712799

DO - 10.1080/21870764.2020.1712799

M3 - Article

AN - SCOPUS:85077872147

JO - Journal of Asian Ceramic Societies

JF - Journal of Asian Ceramic Societies

SN - 2187-0764

ER -