TY - JOUR
T1 - Controllable antimicrobial properties of silver ion-exchanged niobate and tantalate compounds
AU - Isuru Udakara Withanage, Withanage
AU - Ariyapala, Kuda Durayalage Sulasa Devi
AU - Kumada, Nobuhiro
AU - Takei, Takahiro
AU - Ueda, Mayu
AU - Aizawa, Mamoru
N1 - Funding Information:
This study was partly supported by the JSPS KAKENHI Grant 17H03388.
Publisher Copyright:
© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group on behalf of The Korean Ceramic Society and The Ceramic Society of Japan.
PY - 2022
Y1 - 2022
N2 - We designed pyrochlore-type potassium niobate (KN) and potassium tantalate (KT) by introducing silver ions to improve their antibacterial efficiency. KN and KT samples were used as ion-exchangeable parent compounds, and molten AgNO3 was used for the ion-exchange reaction. The formation of silver ion-exchanged compounds with various molar ratios, which was investigated by X-ray diffraction (XRD), indicated a clear structural transformation of KN after complete ion-exchange. The antibacterial efficacy of these samples was investigated using the colony count method, and the relative antibacterial activity was compared based on the area of the inhibition zone. The results indicated that silver ion-exchanged samples with molar ratios of Ag/Nb = 0.05, 0.44, 0.67, and Ag/Ta = 0.07, 0.44 0.64 exhibited complete (100%) antibacterial activity against Staphylococcus aureus (gram-positive) and Escherichia coli (gram-negative). Among the silver ion-exchanged samples, KAN1 and KAT1 exhibited the highest antibacterial activities because of the controlled release of Ag+ ions through their tunnel structure. In this study, it was found that tunable silver-release properties of pyrochlore-type niobate and tantalate enable the optimization of discharged Ag+ ions, which inhibits the bacterial efficacy in different extents, thus suggesting their use in various biomedical applications.
AB - We designed pyrochlore-type potassium niobate (KN) and potassium tantalate (KT) by introducing silver ions to improve their antibacterial efficiency. KN and KT samples were used as ion-exchangeable parent compounds, and molten AgNO3 was used for the ion-exchange reaction. The formation of silver ion-exchanged compounds with various molar ratios, which was investigated by X-ray diffraction (XRD), indicated a clear structural transformation of KN after complete ion-exchange. The antibacterial efficacy of these samples was investigated using the colony count method, and the relative antibacterial activity was compared based on the area of the inhibition zone. The results indicated that silver ion-exchanged samples with molar ratios of Ag/Nb = 0.05, 0.44, 0.67, and Ag/Ta = 0.07, 0.44 0.64 exhibited complete (100%) antibacterial activity against Staphylococcus aureus (gram-positive) and Escherichia coli (gram-negative). Among the silver ion-exchanged samples, KAN1 and KAT1 exhibited the highest antibacterial activities because of the controlled release of Ag+ ions through their tunnel structure. In this study, it was found that tunable silver-release properties of pyrochlore-type niobate and tantalate enable the optimization of discharged Ag+ ions, which inhibits the bacterial efficacy in different extents, thus suggesting their use in various biomedical applications.
KW - Antibacterial activity
KW - ceramics
KW - hydrothermal
KW - ion-exchange
KW - pyrochlore-type
UR - http://www.scopus.com/inward/record.url?scp=85122138542&partnerID=8YFLogxK
U2 - 10.1080/21870764.2021.2006877
DO - 10.1080/21870764.2021.2006877
M3 - Article
AN - SCOPUS:85122138542
VL - 10
SP - 49
EP - 57
JO - Journal of Asian Ceramic Societies
JF - Journal of Asian Ceramic Societies
SN - 2187-0764
IS - 1
ER -