Association between reactogenicity and SARS-CoV-2 antibodies after the second dose of the BNT162b2 COVID-19 vaccine

Shohei Yamamoto, Ami Fukunaga, Akihito Tanaka, Junko S. Takeuchi, Yosuke Inoue, Moto Kimura, Kenji Maeda, Gohzoh Ueda, Tetsuya Mizoue, Mugen Ujiie, Wataru Sugiura, Norio Ohmagari

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

High vaccine reactogenicities may reflect stronger immune responses, but the epidemiological evidence for coronavirus disease 2019 (COVID-19) vaccines is sparse and inconsistent. We observed that a fever of ≥38℃ after two doses of the BNT162b2 vaccine was associated with higher severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike IgG titers.

Original languageEnglish
Pages (from-to)1924-1927
Number of pages4
JournalVaccine
Volume40
Issue number13
DOIs
Publication statusPublished - 18 Mar 2022

Keywords

  • BNT162b2 vaccine
  • Fever
  • Reactogenicity
  • SARS-CoV-2
  • Spike IgG titer

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